Louisville Cardinals vs Florida State Seminoles
FSU
3-2
LOU
2-3 Frequently Asked Questions
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Florida State Seminoles vs Louisville Cardinals: Betting Line, Odds & Head-to-Head Breakdown
NCAAF · 2026 Season · Odds via DraftKings
This game is currently in progress, in the 1st period. The Florida State Seminoles are leading 7-0.
Heading into this NCAAF matchup, DraftKings lists the Louisville Cardinals as the favorite at LOU -4, with the Florida State Seminoles sitting as the underdog on the moneyline. The point spread currently sits at -4, and the over/under total for the game is set at 60.5, giving an early read on how competitive, and how high-scoring, oddsmakers expect this game to be.
Season-series history between the Florida State Seminoles and Louisville Cardinals isn't available for this matchup yet, so there's no head-to-head trend to lean on heading into game day.
Season-long standings context for both sides isn't meaningful yet at this point in the schedule, but the early betting line already gives a decent snapshot of how oddsmakers expect this NCAAF matchup to unfold.
Betting lines, like win probabilities, are a snapshot, not a forecast set in stone, and they can shift right up until the 7:05 - 1st Quarter start time as injury news, weather, and public money move the market. This page will keep reflecting the latest numbers as they update, so it's worth a final check before Florida State Seminoles and Louisville Cardinals actually take the field.
Odds are for informational purposes only and are subject to change. Please gamble responsibly.