DEN
4-2 
ARI
2-4 Team Leaders
Arizona Cardinals
J. Brissett
J. Love
T. McBride
B. Baker
M. Wilson Sr.
Denver Broncos
B. Nix
J.K. Dobbins
J. Waddle
Z. Allen
A. Singleton
Recent Form
Arizona Cardinals
Denver Broncos
Division Standings
2026 AFC West Standings
| Team | W | L | T | PCT | PF | PA | Any |
|---|---|---|---|---|---|---|---|
Kansas City
|
5 | 0 | 0 | 1.000 | 140 | 83 | 5-0 |
|
Denver
|
4 | 2 | 0 | .667 | 114 | 125 | 4-2 |
Las Vegas
|
3 | 3 | 0 | .500 | 162 | 162 | 3-3 |
Los Angeles
|
0 | 6 | 0 | .000 | 90 | 151 | 0-6 |
2026 NFC West Standings
| Team | W | L | T | PCT | PF | PA | Any |
|---|---|---|---|---|---|---|---|
San Francisco
|
6 | 0 | 0 | 1.000 | 177 | 110 | 6-0 |
Seattle
|
3 | 3 | 0 | .500 | 148 | 122 | 3-3 |
|
Arizona
|
2 | 4 | 0 | .333 | 126 | 178 | 2-4 |
Los Angeles
|
2 | 4 | 0 | .333 | 135 | 138 | 2-4 |
Injured Players
Arizona Cardinals
| Player | Status | Est. Return |
|---|---|---|
|
Out | 2026-11-01 |
|
Out | 2026-11-01 |
|
Questionable | 2026-10-25 |
|
|
Questionable | 2026-10-25 |
|
Questionable | 2026-10-25 |
Denver Broncos
| Player | Status | Est. Return |
|---|---|---|
|
Out | 2026-11-01 |
|
Out | 2026-11-01 |
|
Out | 2026-11-01 |
|
Injured Reserve | 2026-10-25 |
|
Questionable | 2026-10-25 |
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Denver Broncos vs Arizona Cardinals: Betting Line, Odds & Head-to-Head Breakdown
NFL · 2026 Season · Odds via DraftKings
As of now, this game hasn't started yet. It's scheduled for 10/25 - 4:05 PM EDT at State Farm Stadium. Check back once the game is underway for live score updates.
Heading into this NFL matchup, DraftKings lists the Denver Broncos as the favorite at DEN -4.5, with the Arizona Cardinals sitting as the underdog on the moneyline. The point spread currently sits at 4.5, and the over/under total for the game is set at 43.5, giving an early read on how competitive, and how high-scoring, oddsmakers expect this game to be.
Season-series history between the Denver Broncos and Arizona Cardinals isn't available for this matchup yet, so there's no head-to-head trend to lean on heading into game day.
Interestingly, the betting market and ESPN's statistical Matchup Predictor are in agreement here, both point to the Denver Broncos as the side more likely to come out on top, with the model putting their win probability at 69%. When the numbers and the odds line up this closely, it's usually a sign the gap between these two teams is real, not just a betting-market quirk.
That betting line lines up with what the standings show. The Denver Broncos currently carry a .667 win percentage on the season, compared to .333 for the Arizona Cardinals. Whether that gap on paper translates to the scoreboard is a different question entirely, standings measure a whole season, while a single game can turn on one swing, one drive, or one bad quarter.
Betting lines, like win probabilities, are a snapshot, not a forecast set in stone, and they can shift right up until the 10/25 - 4:05 PM EDT start time as injury news, weather, and public money move the market. This page will keep reflecting the latest numbers as they update, so it's worth a final check before Denver Broncos and Arizona Cardinals actually take the field.
Odds are for informational purposes only and are subject to change. Please gamble responsibly.