NE
2-2 
BUF
3-1 Team Leaders
Buffalo Bills
J. Allen
J. Cook III
K. Coleman
E. Oliver
D. Williams
New England Patriots
D. Maye
D. Maye
H. Henry
E. Ponder
R. Spillane
Division Standings
2026 AFC East Standings
| Team | W | L | T | PCT | PF | PA | Any |
|---|---|---|---|---|---|---|---|
|
Buffalo
|
3 | 1 | 0 | .750 | 127 | 107 | 3-1 |
|
New England
|
2 | 2 | 0 | .500 | 65 | 77 | 2-2 |
New York
|
1 | 3 | 0 | .250 | 76 | 84 | 1-3 |
Miami
|
0 | 3 | 0 | .000 | 36 | 86 | 0-3 |
Injured Players
Buffalo Bills
| Player | Status | Est. Return |
|---|---|---|
|
Questionable | 2026-10-04 |
|
|
Questionable | 2026-10-04 |
|
Questionable | 2026-10-04 |
|
Doubtful | 2026-10-04 |
|
Out | 2026-10-12 |
New England Patriots
| Player | Status | Est. Return |
|---|---|---|
|
Questionable | 2026-10-04 |
|
Questionable | 2026-10-04 |
|
Questionable | 2026-10-04 |
|
Out | 2026-10-11 |
|
Out | 2026-10-11 |
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New England Patriots vs Buffalo Bills: Betting Line, Odds & Head-to-Head Breakdown
NFL · 2026 Season · Odds via Draft Kings
This game has ended. The New England Patriots defeated the Buffalo Bills, 29-26. You can find the full box score and recap above.
Heading into this NFL matchup, Draft Kings lists the Buffalo Bills as the favorite at BUF -7, with the New England Patriots sitting as the underdog on the moneyline. The point spread currently sits at -7, and the over/under total for the game is set at 49.5, giving an early read on how competitive, and how high-scoring, oddsmakers expect this game to be.
Season-series history between the New England Patriots and Buffalo Bills isn't available for this matchup yet, so there's no head-to-head trend to lean on heading into game day.
That betting line lines up with what the standings show. The New England Patriots currently carry a .500 win percentage on the season, compared to .750 for the Buffalo Bills. Whether that gap on paper translates to the scoreboard is a different question entirely, standings measure a whole season, while a single game can turn on one swing, one drive, or one bad quarter.
Betting lines, like win probabilities, are a snapshot, not a forecast set in stone, and they can shift right up until the Final start time as injury news, weather, and public money move the market. This page will keep reflecting the latest numbers as they update, so it's worth a final check before New England Patriots and Buffalo Bills actually take the field.
Odds are for informational purposes only and are subject to change. Please gamble responsibly.