TEN
1-5 
IND
2-4 Team Leaders
Indianapolis Colts
D. Jones
J. Taylor
K. Allen
A. Davis-Gaither
Tennessee Titans
C. Ward
T. Pollard
C. Tate
J. Simmons
A. Hooker
Division Standings
2026 AFC South Standings
| Team | W | L | T | PCT | PF | PA | Any |
|---|---|---|---|---|---|---|---|
Jacksonville
|
4 | 2 | 0 | .667 | 154 | 104 | 4-2 |
|
Indianapolis
|
2 | 4 | 0 | .333 | 144 | 164 | 2-4 |
Houston
|
2 | 4 | 0 | .333 | 144 | 143 | 2-4 |
|
Tennessee
|
1 | 5 | 0 | .167 | 84 | 129 | 1-5 |
Injured Players
Indianapolis Colts
| Player | Status | Est. Return |
|---|---|---|
|
Questionable | 2026-10-18 |
|
Questionable | 2026-10-18 |
|
Questionable | 2026-10-25 |
|
Out | 2026-10-25 |
|
Out | 2026-10-25 |
Tennessee Titans
| Player | Status | Est. Return |
|---|---|---|
|
Questionable | 2026-10-18 |
|
Out | 2026-10-25 |
|
Out | 2026-10-25 |
|
Out | 2026-10-25 |
|
Out | 2026-10-25 |
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Tennessee Titans vs Indianapolis Colts: Betting Line, Odds & Head-to-Head Breakdown
NFL · 2026 Season · Odds via Draft Kings
This game has ended. The Tennessee Titans defeated the Indianapolis Colts, 26-20. You can find the full box score and recap above.
Heading into this NFL matchup, Draft Kings lists the Indianapolis Colts as the favorite at IND -6.5, with the Tennessee Titans sitting as the underdog on the moneyline. The point spread currently sits at -6.5, and the over/under total for the game is set at 43.5, giving an early read on how competitive, and how high-scoring, oddsmakers expect this game to be.
Season-series history between the Tennessee Titans and Indianapolis Colts isn't available for this matchup yet, so there's no head-to-head trend to lean on heading into game day.
That betting line lines up with what the standings show. The Tennessee Titans currently carry a .167 win percentage on the season, compared to .333 for the Indianapolis Colts. Whether that gap on paper translates to the scoreboard is a different question entirely, standings measure a whole season, while a single game can turn on one swing, one drive, or one bad quarter.
Betting lines, like win probabilities, are a snapshot, not a forecast set in stone, and they can shift right up until the Final start time as injury news, weather, and public money move the market. This page will keep reflecting the latest numbers as they update, so it's worth a final check before Tennessee Titans and Indianapolis Colts actually take the field.
Odds are for informational purposes only and are subject to change. Please gamble responsibly.