Green Bay Packers vs Detroit Lions: Betting Line, Odds & Head-to-Head Breakdown

NFL · 2026 Season · Odds via DraftKings

As of now, this game hasn't started yet. It's scheduled for 10/25 - 4:25 PM EDT at Ford Field. Check back once the game is underway for live score updates.

Heading into this NFL matchup, DraftKings lists the Detroit Lions as the favorite at DET -3.5, with the Green Bay Packers sitting as the underdog on the moneyline. The point spread currently sits at -3.5, and the over/under total for the game is set at 55.5, giving an early read on how competitive, and how high-scoring, oddsmakers expect this game to be.

Season-series history between the Green Bay Packers and Detroit Lions isn't available for this matchup yet, so there's no head-to-head trend to lean on heading into game day.

Interestingly, the betting market and ESPN's statistical Matchup Predictor are in agreement here, both point to the Detroit Lions as the side more likely to come out on top, with the model putting their win probability at 59%. When the numbers and the odds line up this closely, it's usually a sign the gap between these two teams is real, not just a betting-market quirk.

That betting line lines up with what the standings show. The Green Bay Packers currently carry a .667 win percentage on the season, compared to .600 for the Detroit Lions. Whether that gap on paper translates to the scoreboard is a different question entirely, standings measure a whole season, while a single game can turn on one swing, one drive, or one bad quarter.

Betting lines, like win probabilities, are a snapshot, not a forecast set in stone, and they can shift right up until the 10/25 - 4:25 PM EDT start time as injury news, weather, and public money move the market. This page will keep reflecting the latest numbers as they update, so it's worth a final check before Green Bay Packers and Detroit Lions actually take the field.

Odds are for informational purposes only and are subject to change. Please gamble responsibly.